Thrombasthenia (Thrombasthenid)

Thrombasthenia is a rare hereditary blood disease that manifests itself in impaired platelet function. Although the number of platelets in the blood remains unchanged, their ability to clot is significantly reduced. This means that if there is trauma or other damage to the blood vessels, bleeding in patients with thrombasthenia can be significantly increased.

Symptoms of the disease are similar to those observed in other diseases associated with impaired platelet function, such as thrombocytopenic purpura. Patients with thrombasthenia may experience bruising and bleeding, as well as increased bleeding from wounds and injuries.

Thrombasthenia is a hereditary disease that is passed from parents to children. The genetic mutations that lead to thrombasthenia are on chromosome 17 and involve a protein called glycoprotein IIb/IIIa (GPIIb/IIIa). This protein plays an important role in the blood clotting process as it helps platelets adhere and form clots.

Thrombasthenia is diagnosed using special blood clotting tests, as well as genetic studies. Treatment is aimed at reducing the risk of bleeding and may include platelet transfusions and medications that help improve blood clotting.

In conclusion, thrombasthenia is a rare hereditary disorder that results in impaired platelet function and increased bleeding. Symptoms of the disease are similar to those observed in other diseases associated with impaired platelet function. Diagnosis of the disease is carried out using special blood clotting tests and genetic studies. Treatment is aimed at reducing the risk of bleeding and may include platelet transfusions and medications that help improve blood clotting. If you suspect thrombasthenia, you should consult a hematologist for diagnosis and treatment.

**Thrombasthenia** is a genetic disorder of primary hemostasis, characterized by a decrease in the aggregation function of blood platelets (platelets). Red blood cells and white blood cells are involved in this disease to a much lesser extent. The most common is isolated thrombocytopathy, in which the leading mechanism of changes in the adhesive and aggregation functions of blood plates is not identified, but a Krail-Lane study reveals a defect in platelet aggregation after induction with adrenaline (24%).

Thrombocytopathy and thrombasthenia Thrombocytopathy and thrombocytopathy (aka hypo- and thrombopenia) are no less common than thrombocytopenia, but have their own characteristics and treatment.

1) Platelets with abnormal functional properties. This means that they are almost identical in size and weight, and have normal or increased hemoglobin levels. One of the characteristics of these cells is that they change after damage, when healthy elements (normal donor platelets) react to it. These same cells are unable to do this, and if platelets are damaged, they do not form a clot. This function is impaired in children from

**Thrombocytopathy (thrombasthesia)**, or thrombopathy, is a hereditary disease that manifests itself as impaired platelet function with a possible increase or decrease in the number of blood platelets. The disease can occur in two directions: * thrombocytosis - the platelet content exceeds the norm; * thrombocytopenia (or thrombocytopenia) - platelet levels are below normal.