Thrombocytopathy Constitutional

What is hereditary thrombocytopenia?

Inheritance of congenital thrombocytopenia occurs in an autosomal recessive manner. This means that the defective gene occurs in each of the human cells that carry mutations in their genome from both parents, and not just in the case of mutations in one cell

Constitutional thrombocytopenia is a hematological disorder accompanied by increased bleeding, stopping bleeding or ulcerative bleeding. A constitutional defect in the aggregation of blood platelets leads to their aggregation only in response to specific stimuli (adhesion on the surface of the vascular wall). This may be accompanied by an increase in blood viscosity, hemorrhagic phenomena (bruises, nosebleeds), and a decrease in blood clotting is also observed.

- Platelets are the most important elements of the blood, which perform the function of regulating blood in the blood vessels.

- In the case of constitutional thrombocytopathy, there is a disruption in the production of platelets or their functions in the normal blood flow. This can lead to various forms of cardiovascular disorders and circulatory problems.

History of thrombocytopenia-thrombocytopenic purpura, thrombocythemia myelolytic syndrome, thrombotic platelet purpura Wiskott Aldrich syndrome, mycoplasmic purpura Platelets, caused by abuse of analgesics, antiplatelet agents, bone marrow injuries, development of tumors cytoconvertible purpura of hereditary origin thrombocytosis is the property of platelet “proteins” to retain in the blood many times the norm thrombopoietin. Decreased platelet production There are many causes for platelet disorders: varying portions of the total platelet count may be destroyed as a result of infection, poor circulation, or kidney disease. Blood clots can also form due to blood viscosity or impaired tissue nutrition.