Urbach-Oppenheim Dyslipoidosis Skin

Urbach–Oppenheim dyslipoids are an inherited skin disorder characterized by excessive formation of lipids in the dermal layers of the skin. This condition is rare, but it can be very serious and lead to serious cosmetic defects.

Urbach - Oppenheim

Urbach Oppenheim is a syndrome of histologically normal epidermis (adult scleredema), characterized by the presence of coarse dilated follicular ducts with an admixture of eosinophilic fatty cells and small fibroblasts. In the early stage, clinically it is scleroderma, limited mainly to the skin of the face (boarding pads). In the late stage, it gradually spreads throughout the body and manifests itself with characteristic morphological changes.

Follicular hyperkeratosis - pathological changes that are manifested by keratinization of follicles in a pathological state, usually present on the skin of the upper and lower extremities, accompanied by itching. Folliculitis is an acute or chronic inflammation of the hair follicle and its mouth. There are acute superficial folliculitis, deep folliculitis and boils. Superficial folliculitis is characterized by an acute onset, an inflammatory lesion in the area of ​​one or more pustular follicles. A rod is released from the pustule, after which it is rejected, leaving a reddish spot or ulcer. The inflammation foci are characterized by pain. Treatment under the supervision of a dermatologist. If severe folliculitis is accompanied by fever and an increase in white blood cells, it can be assumed that it is a consequence of the introduction of pathogens of severe infectious diseases. Actinic keratosis pilaris. It is characterized by alternating phases of pronounced hyperkeratosis associated with involutive phenomena and sluggish incomplete folliculitis with the formation of small warty formations along the midline of the face and other large folds of skin, skin fascia of the extremities, in places of friction with castes of clothing, nipples, skin of the palms and soles. Upon examination, white dry flat plaques or white papules with pityriasis scales are visible. Acral hyperkeratosis as a manifestation of occupational diseases and neurokeratoses in diseases of the nervous system is characterized by hyperkeratosis of the skin on exposed parts of the body, the mobile part of the upper eyelid, zygomatic arches, and anterior chest. The localization and extent of the lesion correspond to the topography of the affected nervous system. The appearance of nail plates of abnormal coloring, deformation and trophic disorders is caused by disturbances in the innervation of the fingers or toes. White, light yellow, gray nails with a smooth surface and thickened edges or yellow, as if squeezed, blurry nails are noted. They are often deformed: concave, convex. Chronic liver diseases (toxic cirrhosis, chronic hepatitis) are often accompanied by hypomelanoid skin and its derivatives, hypotrichosis, and increased fragility of nails. Red (erythromelalgia), blue, purple spots, spider veins appear on the thighs and buttocks, telangiectasia up to 2 cm in diameter. Seborrheic dermatitis. Signs of the disease appear in children in the first months of life, more often in newborns, less often from 4-6 months to one year. The areas most often affected are the folds of the scalp

Urbach-Oppenheim lipoidosis, or dyschromic purpura, is a skin disease characterized by a symmetrical rash of hemorrhagic spots with various shades of purple, red and pink on the skin, which is accompanied by itching. It most often develops on the lower extremities, but can also be localized on the trunk, face and even mucous membranes.

This disorder was first discovered by Urbach and Oppeheim in the early 20th century. They observed this disease in patients suffering from chronic obstructive pulmonary disease as a secondary form of cutaneous hemosiderosis, genetically caused by defective oxygen transport through the blood. The etiology of this pathology still remains unclear, and its exact genetic basis has not yet been established. However, it is now believed that the disease is not a separate type of melasma, but a complex set of inflammatory and metabolic disorders that can arise from various causes.