Amyotrophy Hereditary Neural

Hereditary neural amyotrophy (syn.: muscular atrophy of the peroneal type, Charcot-Marie-Tooth) is a hereditary disease characterized by progressive muscle weakness and atrophy.

Hereditary neural amyotrophy (synonyms: peroneal muscular atrophy, Charcot-Marie-Thomas) is a hereditary neuromuscular disease manifested by gradually progressive peripheral paralysis of the muscles of the distal limbs, shoulder girdle and face, accompanied by weakness in the limbs, muscle atrophy and sensitivity disorders.

The disease is hereditary in nature and is transmitted according to an autosomal dominant type of inheritance linked to the X chromosome.

Currently, more than 100 forms of hereditary neuromuscular diseases have been described, but the vast majority of them still remain unstudied.

Diagnosis of hereditary neural amyotrophy is based on the characteristic clinical picture of the disease, electroneuromyography data, and genetic research. Treatment includes symptomatic therapy, physiotherapeutic treatment, orthopedic correction, and surgery.

The prognosis for hereditary neural amyotrophy depends on the form of the disease. In some forms, it is possible to maintain working capacity for a long time, but other forms of the disease are characterized by the development of disability.

Amyotrophy is a hereditary disease of the central nervous system. A disease of the first half of human life, characterized by damage to motor neurons of the spinal cord, brainstem, medulla and nerves. This is when muscles gradually weaken and lose their function. This often results in loss of the ability to move freely. The disease can begin at any age and develop throughout life. Unfortunately, there is currently no known therapy that can completely stop this process, but there are times when doctors may recommend treatments such as electrical limb stimulation or hormone replacement therapy. Doctors have noticed that positive dynamics are observed among people who engage in physical labor - for example, loaders, fishermen. He also finds a positive effect if the patient is involved in active recreation - playing football, basketball and other games.