Diplegia Spastic Familial

Diplegia (double, bilateral) or disability is a serious orthopedic pathology, which means complete or partial paralysis of both upper and lower extremities. This term refers to lateral spinal cord lesions involving the superior cingulum of the spinal cord D8-S1. The main cause of the disease is rho

Dipplegia is a complex and common neuromuscular disorder that paralyzes the legs. It is also known as spastic diplegia syndrome. This disease is characterized by limited mobility of the legs, leading to immobility. In the case of spastic familial diplegia, the diagnosis may be followed by a syndrome called diplegic cerebral palsy (CP).

Diplegia usually affects children, one of whose parents is themselves a carrier of the disease. This means that at least one identical twin of a person with diplegia must have been their parent at least once. For a complete understanding, you need to know that the appearance of diplegia is associated with certain mutations in a gene located on the X chromosome. Both dominant and recessive genes can also be found here.

Because women receive only one copy of this gene, they have three variants of the disease if they have the recessive gene. The birth of a child with dipplegia in identical twins, especially among male twins, is equally likely, regardless of which mother is a carrier of this disease. However, two daughters with a parent with diplegia are much less likely to have the disease. If the father has two copies of a recessive mutation in a gene on the same chromosome, the likelihood of the disease in more than one child also increases.

The symptoms of diplegia vary widely and depend on the degree of brain damage. One of the most noticeable symptoms is a decrease in muscle activity and leg function, resulting in an inability to walk and maintain balance. Some patients also experience problems with speech and vision. Other signs of diplegia include seizures, problems with coordination and posture, and mood swings.

Treatment of diplegia is carried out comprehensively and includes medical, social and psychological methods. Medicines can be used to reduce muscle tension and pain, but the focus is on physical therapy to help develop weakened muscles and improve motor skills. Social support and psychological assistance are also very important for patients with diplegia.

Diplegia, or double hemiplegia, is one of the variants of tetraplegia (paralysis of all four limbs), characterized by damage to only the legs, which distinguishes it from hemiplegia or triplegia.

Familial diplegia belongs to the group of childhood spinal palsies. It is caused by primary damage to the posterior and lateral parts of the spinal cord as a result of pathology of the dural sac or deep longitudinal interspinous ligaments. Occurs following a birth injury or due to an inflammatory reaction in the area of ​​herpes rashes. It is often hereditary, just like Duchenne muscular dystrophy (M. Duchenne), cystic fibrosis (M. Coxiella), Hirschsprung disease and others. Occurs in 20–50 out of 55,000