Schaefer Syndrome

Schaefer syndrome

Schaefer syndrome, also known as Touraine-Souligny-Gisselbrecht syndrome or Touraine-Hisselbrecht-Schaufer syndrome, is a congenital genetic disease of the skin and hair of unknown origin. It manifests itself as multiple recurrent foci of generalized lentiform alopecia of the skin and generalized hyperkeratosis of the skin of the palms and soles, limited mainly to the head area. It can lead to hypopigmentation of the affected skin areas and recession of the interdental gingival papillae.

Schaefer syndrome

**Schaefer's syndrome** is a hereditary disease that causes changes in the structure of the skin and mucous membranes. This syndrome was discovered and described by the German dermatologist **E. Schäfer**. Translated from German, its name sounds like “congenital hereditary skin pathology.” It was first identified in French married couples and named after them**. Schaefery** is the surname of one of these spouses.

The *symptoms* of this syndrome are as follows:

- *Strong pigmentation*. The skin becomes very dark, and areas with pigmentation practically do not tan when exposed to sunlight. And often any attempts to remove age spots can cause discomfort. This is due to the fact that melanin synthesis is significantly impaired and causes hyperpigmentation.

Content

Preface. 1. History of development 2. Pathological anatomy 3. Clinical picture 4. Treatment 5. Forecast 6. Prevention 7. Conclusion. References

Schaefer syndrome is also called congenital epidermolysis of Sydenham-Schnalder, phalangeal anomalies and congenital polydysplasia of the ectoderm. This is a rare hereditary pathology in which excessive division of cells in the surface layer of the epidermis occurs. In this case, incomplete epithelial membranes grow, and normal skin is absent. Another 1/4 of the first phalanges