Strumpell Spastic Paraplegia

Strumpel-Spastic paraplegia is a hereditary or sporadic disease of the central nervous system from the group of degenerative myelopathies. In the genetic core of the disease, heredity is mediated by the linkage of genes to the X chromosome in women. It manifests itself as non-progressive atrophy of the spinal cord with secondary disruption of conduction in the peripheral nerves; has nonspecific signs of increased levels of nitrogenous substances in the blood (azotorrhea and proteinuria), as well as characteristic skin disorders in the form of neurofibromatosis. The disease is quite rare. The diagnosis is made based on clinical symptoms, results of electroneuromyography, rheography and biochemical blood tests.

Strumpelli paraplegia is a form of Guillain-Barré syndrome, which is characterized by spastic paralysis of the lower extremities with predominant damage to the muscles of the distal legs. The typical clinical picture is observed in patients who have an increase in antibody titer in combination with one or more electroneuromyographic and neurological features: * Reduced or absent M. extensor digitorum brevis and/or M. tibialis posterior • Reduced F-wave amplitudes of M. flexor digitorum communis

With the acute onset of movement disorders, clinical manifestations can be very similar to epidural hematoma, and with early use of prednisolone, the clinical picture quickly regresses. The presence of an IgM antibody titer and a positive serological test for Guillain-Barré syndrome confirms the diagnostic diagnosis of paraplegia.