Duchenne Muscular Dystrophy (Dmd)

Duchenne Muscular Dystrophy (Dmd, Duchenne Muscular Dystrophy) is a severe hereditary muscular dystrophy that occurs predominantly in boys. It is caused by a mutation in the gene responsible for the synthesis of the dystrophin protein.

Due to the lack of dystrophin, muscle fibers become fragile and gradually break down. This leads to weakness and atrophy of muscles, primarily the muscles of the pelvis and shoulder girdle. Over time, dystrophy affects all muscles of the body, including the respiratory and cardiac muscles.

Typical symptoms include frequent falls, trouble climbing stairs and getting up from the floor. Severe muscle weakness and atrophy gradually develops. Without treatment, most patients lose the ability to walk by age 12 and die from complications by age 20.

Treatment is mainly symptomatic and includes physical therapy, braces and orthopedic devices. Clinical trials of gene therapy are underway. Methods to restore dystrophin function in muscle using CRISPR are being explored. The prognosis remains poor despite progress in treatment.

Introduction to the article:

Duchenne muscular dystrophy (also known as DMD) is a rare inherited disorder that affects the muscles. This disease causes muscle weakness and can lead to various complications, including heart failure, respiratory problems and other problems. Treatment for Duchenne dystrophy includes physical therapy, medication, and surgery. In this article we will look at the basic facts and aspects of Dushensin's dystrophy, as well as methods of its treatment