Paterson-Kelly Syndrome

Paterson-Kelly syndrome (PKS) is a rare inherited disorder that causes hearing loss and middle ear development in newborns. It was first described in 1932 by two Scottish doctors, Duncan Patterson and Archibald Kelly.

Paterson-Kelly syndrome is characterized by the presence of extra tissue in the middle ear, which causes it to expand and impede the flow of fluid from the middle ear. This can lead to a middle ear infection and hearing loss in the newborn.

The causes of PKS are unknown, but it is thought to be related to genetic mutations. Paterson and Kelly described cases in which the disease was detected in several members of the same family.

Treatment for PKS includes surgical removal of extra tissue from the middle ear, as well as antibiotics to prevent infections. In some cases, hearing aids may be needed to improve hearing.

Although PKS is a rare condition, it can be diagnosed in newborns and requires immediate treatment. Early detection and treatment can help prevent the development of irreversible complications and improve patients' quality of life.

And so, Paterson-Kelly syndrome is a rare autosomal recessive disease characterized by a combination of sixth nerve palsy and lateral scleroderma. The disease was first described by Douglas R. Paterson in 1912 and by Alana W. Kelly in 1921.

This is a very rare disease that manifests itself in the form of paralysis of the facial nerve, which appears in utero, leading to severe impairment of facial movements. This disease can also cause hearing and vision loss. The disease may