Stewart-Prower Disease

Stewart's - Prower's disease. Stuart-Payor syndrome (intestinal epithelial degeneration syndrome) is a hereditary combined lesion of the gastrointestinal tract, in which typical changes develop in both the esophagus and stomach, duodenum, proximal small intestine and mesenteric lymph nodes. It can also affect the nervous system, eyes and other organs. This disease is very rare; about 50 patients have been registered throughout Europe. Pathological changes can only be detected during post-mortem pathological examination. Symptoms usually appear between the ages of 8 and 9 years. The disease worsens in the cold season. Children complain of abdominal pain, worsening after physical activity, and a feeling of heaviness in the epigastric region. In patients under 2.5 years of age, the stool is liquefied, of a mushy consistency, with unstable feces; before the appearance of loose stools, constipation is noted. From two to four years of age, appetite increases. Parents pay attention to the rapid decrease in body weight against the background of a satisfactory appetite. In children under two years of age, there is a progressive eating disorder, developmental delay, and frequent recurrent obstructive bronchitis. Relatives are afraid for the health of their child and turn to specialists, but the course of the disease increases over the years. Weakness and pallor gradually sets in